Practically Speaking: Neoadjuvant Chemo/IO for Resectable NSCLC

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In this episode, Dr. Adrian Sacher will discuss the perioperative management of NSCLC – focusing on the recently accessible Nivo/Chemo regimen.  He will discuss the practical aspects of incorporating this into daily practice.

Key Opinion Leader: 
Dr. Adrian Sacher
Assistant Professor of Medicine and Immunology
Staff Medical Oncologist and Affiliate Scientist
Princess Margaret Cancer Centre
University of Toronto

Host:
Dr. Shaqil Kassam 
skassam@southlakeregional.org 
Medical Oncologist 
Stronach Regional Cancer Centre, Newmarket, Ontario 

Outline:
0:00 - Introduction
2:30 - New standard of Care? 
5:10 - pCR and mPR surrogate for survival
6:55 - Chemobackbone for Chemo Nivo and histology
9:55 - Carbplatin vs. Cisplatin as platinum backbone
12:10 - Pre-surgical Imaging
19:50 - Time from Chemo Nivo to Surgery
22:50 - Surgical Issues
26:30 - Stage III - Checkmate 816 vs. Pacific
32:20 - PDL1 status and this regimen? 
34:20 - Further adjuvant systemic therapy post Checkmate 816 

Previous Episodes: 
Gastric Cancer: http://tobtr.com/12051154
NGS: http://tobtr.com/12072620
Paxlovid and Cancer treatment:http://tobtr.com/12090165
Billiary Tract Cancers: http://tobtr.com/12135321
Adjuvant immunotherapy for kidney cancers: http://tobtr.com/12149885